Abstract
This article explores the clinical and demographic characteristics of chronic heart failure (CHF) among middle-aged and elderly populations in the Khorezm region of Uzbekistan. The study analyzes the age-related progression, gender differences, and the influence of comorbid conditions such as hypertension, ischemic heart disease, diabetes, and renal dysfunction on the course of CHF. Results indicate that older patients exhibit more severe CHF symptoms, with a higher prevalence of preserved ejection fraction in elderly women and increased renal complications. The findings highlight the need for region-specific approaches to the diagnosis, monitoring, and management of CHF in aging populations.