Systemic Lupus Erythematosus in Children: Clinical and Laboratory Aspects of Diagnosis and Course
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Keywords

systemic lupus erythematosus
autoimmune disease
children
immunological markers
pathogenesis

How to Cite

Z. A., S., D. T., A., N. Ya., F., & A. A., R. (2024). Systemic Lupus Erythematosus in Children: Clinical and Laboratory Aspects of Diagnosis and Course. Excellencia: International Multi-Disciplinary Journal of Education (2994-9521), 2(7), 68-75. https://doi.org/10.5281/

Abstract

Systemic lupus erythematosus (SLE) is a systemic autoimmune disease of unknown etiology characterized by the hyperproduction of organ-nonspecific autoantibodies to various components of the cell nucleus, leading to immune-inflammatory damage to tissues and internal organs. Research aim: to study the role of immunological markers in the pathogenesis of SLE development in children. Materials and methods: data collection was conducted between 2022-2024 at the Tashkent Pediatric Medical Institute clinic. Preliminary studies show that the imbalance of immunological markers and the increase in autoantibodies are associated with the severity and recurrent nature of the disease.

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