THE ROLE OF INTERLEUKIN 17A AND INTERLEUKIN 17E (IL25) IN THE PROGRESSION OF LIVER FIBROSIS IN PATIENTS WITH HEPATITIS C VIRUS INFECTION

Abstract

The chronic infection with the hepatitis C virus (HCV) is regarded as one of the main health problem. Globally, around 180 million people had an HCV infection. With a new evidence supporting the involvement of IL-17A and IL-17E (IL25) in the development of chronic HCV infection as the host immunity plays a significant role in this infection, since the high levels of these two types may raise the risk of developing liver fibrosis in the chronic HCV infection, so our goal was to estimate the involvement of interleukins in the liver fibrosis in patients with chronic HCV infection and this study estimated the fibrosis in liver by measuring the levels of IL-17A and IL-17E as c markers for fibrosis which contributes to the development of liver fibrosis.