Abstract
This study explores the prevalence and characteristics of cognitive impairment among Parkinson’s disease patients in the Khorezm region of Uzbekistan. It highlights the major clinical and demographic factors influencing cognitive decline, including age, disease duration, and socio-economic status. The research underscores the urgent need for early screening and integrated multidisciplinary care strategies tailored to regional needs. By analyzing both motor and non-motor symptoms in a local context, the study provides valuable insights for healthcare practitioners and policymakers aiming to enhance the management and quality of life for Parkinson’s patients in Central Asia.