Bioseparation and Purification of Hepatotoxins Microcystin–LR from Cyanobacteria Species Westiellopsis Prolifica

Abstract

The presents study included bioseparation and purification of hepatotoxins microcystin-LR from cyanobacteria species westeillopsis prolifica the concentration of toxin was determined by preparative high performance liquid chromatography by comparing peak area and retention time of analytical standard of microcystin-LR with peak area and retention time of extraction of each species of cyanobacteria, the retention time of analytical standard of microcystinLR were 9.55 min and it’s concentration was 10μg/ml, W. prolifica retention time was 9.5 min, it’s concentration was 28.385 µg/ml.