Applying Physical and Engineering Principles to Develop Innovative Medical Devices and Technologies: An Integrated Perspective of General, Applied, and Medical Physics With Medical Device Engineering
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Abstract
Medical technologies encompass the development and application of devices and tools to support or enhance human life through detection, treatment, and prevention. Over past decades, healthcare has witnessed transformative innovations such as 3D-printed prosthetics, nanotechnology-based drug delivery systems, and radio-frequency identification (RFID)–enabled smart implants. The contemporary exploration of emerging physical principles and engineering materials promises to revolutionize healthcare delivery.Historically, medical technology evolved from early humans’ implementation of rudimentary tools and prosthetics to advanced surgical instruments and diagnostic equipment. Such progress often resulted from studies of fundamental physical principles and examination of human physiology and pathology. Medical instruments and tools frequently represent practical applications of physical concepts, including mechanics, thermodynamics, fluid dynamics, and electromagnetism. Conversely, the development of improved medical devices has prompted the emergence of new engineering principles and methodologies in materials, electrical components, and software—collectively driving forward the field of medical technology. Modern innovations encompass smart devices, wearable technology, telemedicine, robotic surgery, printed electronics, implantable materials, and microfluidics. Given the persistent challenges imposed by rising costs, aging populations, and epidemics, continuous advancement in medical technology remains a top priority.The integration of physical principles and engineering materials is therefore a cornerstone of medical technology innovation. Employing these multidisciplinary approaches facilitates the conception and realization of novel tools, instruments, and systems capable of addressing persistent healthcare challenges. Medical technologies whose capabilities surpass the confines of individual engineering disciplines are herein classified as innovative medical technologies.
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O. Braun Benyamin, D. Juvinao, T. Berlinsky, A. Salih et al., "Designing Engineering Solutions to Surgical Problems: How to Translate Physiology to Biomechanics," 2022. ncbi.nlm.nih.gov
Díaz Lantada, J. Javier Serrano Olmedo, A. Ros Felip, J. Jiménez Fernández et al., "CDIO Experiences in Biomedical Engineering: Preparing Spanish Students for the Future of Medicine and Medical Device Technology," 2016. [PDF]
Z. Jin, C. He, J. Fu, Q. Han et al., "Balancing the customization and standardization: exploration and layout surrounding the regulation of the growing field of 3D-printed medical devices in China," 2022. ncbi.nlm.nih.gov
J. C. Chiao, J. M. Goldman, D. A. Heck, P. Kazanzides et al., "Metrology and Standards Needs for Some Categories of Medical Devices," 2008. ncbi.nlm.nih.gov
J. Kurian, "Harnessing Aerospace Fluid Mechanics and Cavitation for Biomedical Engineering: Advancing Non-Invasive Therapies, Drug Delivery, and Medical Devices," 2025 Regional Student Conferences, 2025. aiaa.org
Garg, B. Akkinepally, J. Sarkar, and S. K. Pattanayek, "Emerging perspectives in non-Newtonian fluid dynamics: Research gaps, evolving methods, and conceptual limitations," Physics of Fluids, 2025. chemrxiv.org
M. Ghalambaz, M. A. Sheremet, M. A. Khan, "Physics-informed neural networks (P INNs): application categories, trends and impact," *International Journal of Heat and Fluid Flow*, 2024. researchgate.net
R. Cocchieri, B. van de Wetering, M. Stijnen, R. Riezebos et al., "The Impact of Biomedical Engineering on the Development of Minimally Invasive Cardio-Thoracic Surgery," 2021. ncbi.nlm.nih.gov
U. M. B. E. R. T. O. LUCIA, "Bioengineering thermodynamics of biological cells," 2015. [PDF]
U. M. B. E. R. T. O. LUCIA, "Bioengineering Thermodynamics: An Engineering Science for Thermodynamics of Biosystems," 2015. [PDF]
B. K. Lee, "Computational Fluid Dynamics in Cardiovascular Disease," 2011. ncbi.nlm.nih.gov
M. Siebes and Y. Ventikos, "The Role of Biofluid Mechanics in the Assessment of Clinical and Pathological Observations: Sixth International Bio-Fluid Mechanics Symposium and Workshop, March 28–30, 2008 Pasadena, California," 2010. ncbi.nlm.nih.gov
Y. David and T. Judd, "Evidence-based impact by clinical engineers on global patients outcomes," 2019. ncbi.nlm.nih.gov
"Diagnostic and Therapeutic MEMS (Micro-Electro-Mechanical Systems) Devices for the Identification and Treatment of Human Disease," 2018. [PDF]
J. Loy, "Curious Directions for Product Designers: How technology is affecting medical design practice," 2014. [PDF]
Assadi, P. C. Laussen, A. J. Goodwin, S. Goodfellow et al., "An integration engineering framework for machine learning in healthcare," 2022. ncbi.nlm.nih.gov
Wan An, J. Hwal Shin, S. Y. Kim, J. Kim et al., "Smart Sensor Systems for Wearable Electronic Devices," 2017. ncbi.nlm.nih.gov
K. Yetisen, J. Leonardo Martinez‐Hurtado, B. Ünal, A. Khademhosseini et al., "Wearables in Medicine," 2018. ncbi.nlm.nih.gov
Swaminathan, "AEVUM: Personalized Health Monitoring System," 2018. [PDF]
J. G Greenburg, "Measurement and Description of Dynamics Required for u3ciu3ein vivou3c/iu3e Surgical Robotics via Kinematic Methods," 2013. [PDF]
J. Troccaz, "Medical robotics: where we come from, where we are and where we could go," 2008. [PDF]
N. A. Omoregbe, A. A. Atayero, C. K. Ayo, and O. O. Olugbara, "Design and deployment of hybrid-telemedicine applications," 2015. [PDF]
M. Baschuk, "3D Printing and The Evolution Of Partial Hand Prostheses: My Journey from Theory To Practice," 2023. ncbi.nlm.nih.gov
I. Mavrodontis, I. G. Trikoupis, V. A. Kontogeorgakos, O. D. Savvidou et al., "Point-of-Care Orthopedic Oncology Device Development," 2023. ncbi.nlm.nih.gov
M. Baschuk, "3D Printing and The Evolution Of Partial Hand Prostheses: My Journey from Theory To Practice," Canadian Prosthetics & Orthotics Journal, 2023. nih.gov
G. M. Kim, J. E. Powell, S. A. Lacey, J. A. Butkus et al., "Current and emerging prostheses for partial hand amputation: A narrative review," PM&R, 2023. [HTML]
L. O'Brien, E. Cho, A. Khara, J. Lavranos, "3D-printed custom-designed prostheses for partial hand amputation: Mechanical challenges still exist," *Journal of Hand*, vol. XX, no. YY, pp. ZZ-ZZ, 2021. [HTML]
T. Panagiotou and R. J. Fisher, "Enhanced Transport Capabilities via Nanotechnologies: Impacting Bioefficacy, Controlled Release Strategies, and Novel Chaperones," 2011. ncbi.nlm.nih.gov
Sun, Z. Yang, and L. Teng, "Nanotechnology and Microtechnology in Drug Delivery Systems," 2020. ncbi.nlm.nih.gov
Sonamuthu, "Applications of Nanotechnology in Drug Delivery Systems," 2019. [PDF]
H Ledet, B. Liddle, K. Kradinova, and S. Harper, "Smart implants in orthopedic surgery, improving patient outcomes: a review," 2018. ncbi.nlm.nih.gov
Abyzova, E. Dogadina, R. D. Rodriguez, I. Petrov et al., "Beyond Tissue replacement: The Emerging role of smart implants in healthcare," 2023. ncbi.nlm.nih.gov
Craig and M. L. Nagurka, "Multidisciplinary Engineering Systems 2nd and 3rd Year College-Wide Courses," 2010. [PDF]
Ravizza, C. De Maria, L. Di Pietro, F. Sternini et al., "Comprehensive Review on Current and Future Regulatory Requirements on Wearable Sensors in Preclinical and Clinical Testing," 2019. ncbi.nlm.nih.gov
Pagliari, "Design and Evaluation in eHealth: Challenges and Implications for an Interdisciplinary Field," 2007. ncbi.nlm.nih.gov
R. R. Sankaran, J. M. Ameling, A. E.M. Cohn, C. M. Grum et al., "A Practical Guide for Building Collaborations Between Clinical Researchers and Engineers: Lessons Learned From a Multidisciplinary Patient Safety Project," 2020. ncbi.nlm.nih.gov
K. Cheng, C. Lin, and Y. Luan, "From “academic success” to “commercial success”—the model of medical device translation driven by SCI articles," Journal of Orthopaedic Translation, 2025. sciencedirect.com
Y. Ushimaru, T. Katoh, M. Sasaki, T. Hata, M. Hosaka, "Development of medical devices driven by academia-industry collaboration: An internal audit," Surgery, vol. 2025, Elsevier. sciencedirect.com
Dave, D. Vyas, T. Panigrahi, "Barriers to Industry-Academia Collaboration–—A Study With a Focus on the Indian Medical Devices Sector," Journal of Higher Education, 2025. researchgate.net
V. Nangalia, D. R Prytherch, and G. B Smith, "Health technology assessment review: Remote monitoring of vital signs - current status and future challenges," 2010. ncbi.nlm.nih.gov
Tomasic, N. Tomasic, R. Trobec, M. Krpan et al., "Continuous remote monitoring of COPD patients—justification and explanation of the requirements and a survey of the available technologies," 2018. ncbi.nlm.nih.gov
S. Pasricha, "Ethics for Digital Medicine: A Path for Ethical Emerging Medical IoT Design," 2022. [PDF]
Fragopoulos, J. Gialelis, and D. Serpanos, "Security Framework for Pervasive Healthcare Architectures Utilizing MPEG-21 IPMP Components," 2009. ncbi.nlm.nih.gov
S. Ahmed, "BYOD, Personal Area Networks (PANs) and IOT: Threats to Patients Privacy," 2019. [PDF]
E. Szymczak, A. G. Fiks, S. Craig, D. D. Mendez et al., "Access to What for Whom? How Care Delivery Innovations Impact Health Equity," 2023. ncbi.nlm.nih.gov